Hao Jiang, Xueying Li, Zhuoyan Liu, Siyu Luo, Junbin Huang, Chun Chen, Rui Chen *, Fenfang Li *. A microfluidic approach to assess the rheological properties of red blood cells in health and thalassemia.  (Submited)

Yuanyuan Shen^#, Yicong Cai^#, Chaofeng Qiao, Zhihui Liu, Yiluo Xu, Mengni Hu, Ji Zhang, Lin Ma*, Fenfang Li*. A bottom-up approach to understanding ultrasound mediated blood-brain barrier opening using short pulses. (Submited)

Yu Yong ^#, Hao Jiang ^#, Chaofeng Qiao, Zhuoyan Liu, Xiaohan Zhou, Yufeng Zhou, Fenfang Li*. Ultrasonic Modulation of Astrocytic and Neuronal Calcium Dynamics in Mouse Cortex. (Submitted)  https://www.biorxiv.org/content/10.1101/2025.03.03.641164v1

Yu Wang#, Hao Jiang#, Zhenwei Su, Ran Wang, Xinyuan Luo, Lingxiao Zhang, Zhi Ping Xu, Fenfang Li*, Chao He*; The drug resistance feature of acute myeloid leukemia is related to the cell stiffness. Biophysics Reviews, 2025; 6 (2): 021402. https://doi.org/10.1063/5.0244619

Fenfang Li*, Hao Jiang, Jiawei Lin, Chaofeng Qiao, George J. Augustine. Low intensity pulsed ultrasound activates excitatory synaptic networks in cultured hippocampal neurons. Ultrasound in Medicine and Biology, 2025; 51(8):1250-1260  https://www.umbjournal.org/article/S0301-5629(25)00128-0/fulltext

Jiawei Lin, Chaofeng Qiao, Hao Jiang, Yaxin Hu, Wei Liu, Yu Yong, Fenfang Li* (2025). "Reversible Ca2+ signaling and enhanced paracellular transport in endothelial monolayer induced by acoustic bubbles and targeted microbeads." Ultrasonics Sonochemistry 112: 107181. https://doi.org/10.1016/j.ultsonch.2024.107181

Dandan Li #, Yu Yong #, Chaofeng Qiao, Hao Jiang, Jiawei Lin, Jianpeng Wei, Yufeng Zhou, Fenfang Li* (2025). Low intensity pulsed ultrasound dynamically modulates the migration of BV2 microglia. Ultrasound in Medicine and Biology 51(3), 494-507(# co-first author）https://doi.org/10.1016/j.ultrasmedbio.2024.11.010

Journal

Lu Y, Sun Y, Shen Z, Xu X, Ma T, Peng C, Li F, Ning C, Wang J, Liu S, Liu Z, Xu L, Liu W. Thermal-tagging photoacoustic remote sensing flowmetry. Opt Lett. 2024, 49(7):1725-1728

Yu Yong, Yicong Cai, Jiawei Lin, Lin Ma, HongBin Han*,Fenfang Li*. Advancement in Modulation of Brain Extracellular Space and Unlocking its Potential for Intervention

of Neurological Diseases. Med-X. 2024, 2(6) https://doi.org/10.1007/s44258-024-00021-7    

Presentations:

Invited talks:

Fenfang Li, "Ultrasound modulation of vascular endothelial permeability and delivery mechanisms", CUMB2024 & 90th CMEF Ultrasound forum, Shenzhen, Oct 13th, 2024

Fenfang Li. "Low intensity pulsed ultrasound activate excitatory synaptic networks in cultured hippocampal neurons", 11^th WACBE World Congress on Bioengineering, The Hong Kong Polytechnic University, Hong Kong, Aug 4-7th, 2024

Oral:

Fenfang Li. "Evaluation of acoustic parameters on the microbubble dynamics within small channels of different width", 12th CAVITATION SYMPOSIUM (CAV2024), Maich Conference Centre, Chania, Greece, June 2-5th, 2024

Journal

Hao Shen, Xiangru Liu, Qi Cui, Yunxu Sun, Bing Yang, Fenfang Li, Xiaochuan Xu, Zhengjun Liu, and Wei Liu, "Limited view correction in low-optical-NA photoacoustic microscopy," Opt. Lett. 48, 5627-5630 (2023)

Presentations:

Invited talks:

Fenfang Li, “Cavitation bubble on a chip: probing the biophysics and mechanotransduction of cells", International Congress on Ultrasonics in Beijing (the 2023 ICUBEIJING), Beijing Friendship Hotel, Beijing, China, 18 Sept. to 21 Sept. 2023.

Fenfang Li, “Single Cell Hydrodynamic Stretching and Microsieve Filtration Reveal Genetic, Phenotypic and Treatment-Related Links to cellular Deformability”, 3^rd International conference on biomaterials, bio-design and manufacturing (BDMC, 2023), National University Singapore, Singapore, 6-8^th August, 2023.

Journal

Yicong Cai; Kexin Fan; Jiawei Lin; Lin Ma; Fenfang Li* ; Advances in BBB on Chip and Application for Studying Reversible Opening of Blood–Brain Barrier by Sonoporation, Micromachines, 2023, 14(1): 112 (Online in 2022)

Presentations:

Oral:

Fenfang Li. Low Intensity Pulsed Ultrasound Excites Synaptic Transmission in Hippocampal Neuron Networks. 21th International Symposium of Therapeutic Ultrasound (ISTU). Toronto, Canada. June 7-10th, 2022.

Fenfang Li. Integrin Ligation Mediates Ca²⁺ Response Elicited by Cavitation Microbubble. 21th International Symposium of Therapeutic Ultrasound (ISTU). Toronto, Canada. June 7-10th, 2022.

Fenfang Li*; Igor Cima; Jess Honganh Vo; Min-Han Tan; Claus Dieter Ohl*; Single cell hydrodynamic stretching and microsieve filtration reveal genetic, phenotypic and treatment-related links to cellular deformability, Micromachines, 2020, 11(5): 486.

Fenfang Li; Chen Yang; Fang Yuan; Defei Liao; Thomas Li; Farshid Guilak; Pei Zhong*; Dynamics and mechanisms of intracellular calcium waves elicited by tandem bubble induced jetting flow, Proceedings of the National Academy of Sciences , 2018, 115(3): E353-E362.

M. Mohammadzadeh; F. Li and C. D. Ohl, “Shearing flow from transient bubble oscillations in narrow gaps,” Physical Review Fluids 2 (1), 014301 (2017)

F. Li*, R.Gonzalez-Avila, D.M. Nguyen, C.D. Ohl*, “Oscillate boiling from microheaters,” Physical Review Fluids 2 (1), 014007 (2017)

F. Li*, F. Yuan, G. Sankin, C. Yang, P. Zhong*, “A Microfluidic System with Surface Patterning for Investigating Cavitation Bubble(s)-Cell Interaction and Resultant Bioeffects at Single Cell Level,” Journal of Visualized Experiments, 119 (2017) (corresponding author)

Fenfang Li*; Chon U Chan; Claus Dieter Ohl* ; Rebuttal to a comment by Richard E. Waugh on our article "Yield strength of human erythrocyte membranes to impulsive stretching", Biophysical Journal, 2014, 106: 1832-1833

.

Fenfang Li*, Chon U Chan, Claus Dieter Ohl*; Yield strength of human erythrocyte membranes to impulsive stretching, Biophysical journal, 2013, 105 (4), 872-879

Tandiono Tandiono; Evert Klaseboer; Siew-Wan Ohl; Dave Siak-Wei Ow; Andre Boon-Hwa Choo;Fenfang Li; Claus-Dieter Ohl* ; Resonant stretching of cells and other elastic objects from transient cavitation, Soft Matter, 2013, 9: 8687-8697

Van der Kroon, I., Quinto-Su, P.A., F. Li, Ohl, C.D., “Acoustically driven cavitation cluster collapse in planar geometry,” Physical Review E, 82, 066311 (2010)